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- B0d1830521f3e8fd1fcdb5595a2a85dd2 NCIT_P378 "NCI" @default.
- B0d1830521f3e8fd1fcdb5595a2a85dd2 type Axiom @default.
- B0d1830521f3e8fd1fcdb5595a2a85dd2 annotatedProperty IAO_0000115 @default.
- B0d1830521f3e8fd1fcdb5595a2a85dd2 annotatedSource NCIT_C61653 @default.
- B0d1830521f3e8fd1fcdb5595a2a85dd2 annotatedTarget "A selective beta-1 adrenergic receptor antagonist with antihypertensive activity and devoid of intrinsic sympathomimetic activity. Bisoprolol selectively and competitively binds to and blocks beta-1 adrenergic receptors in the heart, thereby decreasing cardiac contractility and rate. This leads to a reduction in cardiac output and lowers blood pressure. In addition, bisoprolol prevent the release of renin, a hormone secreted by the kidneys that causes constriction of blood vessels." @default.