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- B0d1e914779da42fb915e4283e15c6ac3 NCIT_P378 "NCI" @default.
- B0d1e914779da42fb915e4283e15c6ac3 type Axiom @default.
- B0d1e914779da42fb915e4283e15c6ac3 annotatedProperty IAO_0000115 @default.
- B0d1e914779da42fb915e4283e15c6ac3 annotatedSource NCIT_C78187 @default.
- B0d1e914779da42fb915e4283e15c6ac3 annotatedTarget "A glycoengineered, fully human IgG1 monoclonal antibody directed against the extracellular domain of the human CD70 molecule with potential antineoplastic activity. Anti-CD70 fully human monoclonal antibody MDX-1411 selectivity binds to the extracellular domain of CD70, which may induce an antibody-dependent cellular cytotoxicity (ADCC) response against CD70-expressing tumor cells. CD70, the ligand for the costimulatory receptor CD27 and a member of the tumor necrosis factor (TNF) family, is found on renal cell carcinoma (RCC) cells among other cancer cell types." @default.