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- B0d82312c885243eff10b8150fcfdf804 date_retrieved "2012-09-17" @default.
- B0d82312c885243eff10b8150fcfdf804 external_class "VHOG:0001429" @default.
- B0d82312c885243eff10b8150fcfdf804 ontology "VHOG" @default.
- B0d82312c885243eff10b8150fcfdf804 source "DOI:10.1016/S0012-1606(03)00308-7 Field HA, Dong PD, Beis D, Stainier DY, Formation of the digestive system in zebrafish. II. Pancreas morphogenesis. Developmental Biology (2003), DOI:10.2337/diabetes.49.2.225 Polak M, Bouchareb-Banaei L, Scharfmann R, Czernichow P, Early pattern of differentiation in the human pancreas. Diabetes (2000)" @default.
- B0d82312c885243eff10b8150fcfdf804 source "http://bgee.unil.ch/" @default.
- B0d82312c885243eff10b8150fcfdf804 type Axiom @default.
- B0d82312c885243eff10b8150fcfdf804 annotatedProperty UBPROP_0000003 @default.
- B0d82312c885243eff10b8150fcfdf804 annotatedSource UBERON_0003924 @default.
- B0d82312c885243eff10b8150fcfdf804 annotatedTarget "In chick, Xenopus laevis, and the teleost fish Medaka, the pancreas develops from three buds that emerge from the gut tube, two from its ventral aspect, and one from its dorsal aspect. In mouse, although there are initially three buds that arise from the gut tube at the point of contact between the endoderm and the vasculature, the pancreas develops from only two of these buds, one dorsal and one ventral. (...) In this study, we use a transgenic zebrafish line (...). We provide evidence for the existence of two distinct pancreatic anlagen - a ventral anterior bud and a dorsal posterior bud - that join to form the definitive pancreas (reference 1); The pancreas develops from the fusion of distinct endoderm-derived dorsal and ventral diverticula. In humans, by day 35 of development, the ventral pancreatic bud begins to migrate backwards and comes into contact and eventually fuses with the dorsal pancreatic bud during the sixth week of development (reference 2).[well established][VHOG]" @default.