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- B0e2f17e55050fa9036a1829e29c0b0fe NCIT_P378 "NCI" @default.
- B0e2f17e55050fa9036a1829e29c0b0fe type Axiom @default.
- B0e2f17e55050fa9036a1829e29c0b0fe annotatedProperty IAO_0000115 @default.
- B0e2f17e55050fa9036a1829e29c0b0fe annotatedSource NCIT_C1559 @default.
- B0e2f17e55050fa9036a1829e29c0b0fe annotatedTarget "The active l-isomer of the racemic mixture of the 5-formyl derivative of tetrahydrofolic acid. Metabolically active, l-leucovorin, also known levoleucovorin, does not require bioactivation by dihydrofolate reductase, an enzyme inhibited by folic acid antagonists. This agent may enhance the effects of fluoropyrimidines by stabilizing their binding to the enzyme thymidylate synthase. (NCI04)" @default.