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- B0fbd4e0b6674e380deff4ef3d7994676 NCIT_P378 "NCI" @default.
- B0fbd4e0b6674e380deff4ef3d7994676 type Axiom @default.
- B0fbd4e0b6674e380deff4ef3d7994676 annotatedProperty IAO_0000115 @default.
- B0fbd4e0b6674e380deff4ef3d7994676 annotatedSource NCIT_C1433 @default.
- B0fbd4e0b6674e380deff4ef3d7994676 annotatedTarget "An orally-active benzimidazole derivative with potential antineoplastic activity. As a retinoic acid metabolism blocking agent, liarozole inhibits cytochrome P450-dependent all-trans-retinoic acid (ATRA)-4-hydroxylase, resulting in an increase in endogenous ATRA production, inhibition of cell proliferation, and induction of cell differentiation. This agent also inhibits aromatase, the enzyme that catalyzes the final, rate-limiting step in estrogen biosynthesis." @default.