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- B0fef61c479c3ba5a0ac5047233685cc5 NCIT_P378 "NCI" @default.
- B0fef61c479c3ba5a0ac5047233685cc5 type Axiom @default.
- B0fef61c479c3ba5a0ac5047233685cc5 annotatedProperty IAO_0000115 @default.
- B0fef61c479c3ba5a0ac5047233685cc5 annotatedSource NCIT_C13253 @default.
- B0fef61c479c3ba5a0ac5047233685cc5 annotatedTarget "A class of morphologically heterogeneous cytoplasmic membrane-bound vesicle in animal and plant tissues characterized by their content of a wide variety of glycoprotein hydrolytic enzymes active at an acid pH and the structure-linked latency of these enzymes. The intracellular functions of lysosomes depend on their lytic potential. The single unit membrane of the lysosome acts as a barrier between the enzymes enclosed in the lysosome and the external substrate. The activity of the enzymes contained in lysosomes is limited or nil unless the vesicle in which they are enclosed is ruptured. Such rupture serves to digest exogenous material, such as bacteria, as well as effete organelles of the cells and is supposed to be under metabolic (hormonal) control." @default.