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- B0ff5b5087fd2ed6e8ecad59e0722e2f4 NCIT_P378 "NCI" @default.
- B0ff5b5087fd2ed6e8ecad59e0722e2f4 type Axiom @default.
- B0ff5b5087fd2ed6e8ecad59e0722e2f4 annotatedProperty IAO_0000115 @default.
- B0ff5b5087fd2ed6e8ecad59e0722e2f4 annotatedSource NCIT_C152206 @default.
- B0ff5b5087fd2ed6e8ecad59e0722e2f4 annotatedTarget "The acetate form of rezafungin, a next-generation, semi-synthetic, cyclic lipopeptide and echinocandin derivative, with potential antifungal activity. Upon administration, rezafungin inhibits the fungal specific enzyme 1,3-beta-D-glucan synthase, which is essential for fungal cell wall synthesis, and results in decreased synthesis of beta(1,3)-D-glucan. This weakens the fungal cell wall thereby causing osmotic lysis, fungal cell wall rupture and fungal cell death." @default.