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- B104905838acca20c65f81675c461bd3d NCIT_P378 "NCI" @default.
- B104905838acca20c65f81675c461bd3d type Axiom @default.
- B104905838acca20c65f81675c461bd3d annotatedProperty IAO_0000115 @default.
- B104905838acca20c65f81675c461bd3d annotatedSource NCIT_C29531 @default.
- B104905838acca20c65f81675c461bd3d annotatedTarget "A nitrogenous compound containing a carbonyl group attached to two amine groups with osmotic diuretic activity. In vivo, urea is formed in the liver via the urea cycle from ammonia and is the final end product of protein metabolism. Administration of urea elevates blood plasma osmolality, resulting in enhanced flow of water from tissues, including the brain, cerebrospinal fluid and eye, into interstitial fluid and plasma, thereby decreasing pressure in those tissues and increasing urine outflow." @default.