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- B104bf95e4904050b7cee1d12a5306a51 NCIT_P378 "NCI" @default.
- B104bf95e4904050b7cee1d12a5306a51 type Axiom @default.
- B104bf95e4904050b7cee1d12a5306a51 annotatedProperty IAO_0000115 @default.
- B104bf95e4904050b7cee1d12a5306a51 annotatedSource NCIT_C65754 @default.
- B104bf95e4904050b7cee1d12a5306a51 annotatedTarget "A long-acting beta-adrenergic receptor agonist with bronchodilator activity. Formoterol selectively binds to beta-2 adrenergic receptors in bronchial smooth muscle, thereby activating intracellular adenyl cyclase, an enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cAMP). Increased cAMP levels cause relaxation of bronchial smooth muscle, relieve bronchospasms, improve mucociliary clearance and reduce mediator substance release from inflammatory cells, especially from mast cells." @default.