Matches in Ubergraph for { <https://frink.apps.renci.org/.well-known/genid/B10838ad24bd36a68ae8764010504857f> ?p ?o ?g. }
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- B10838ad24bd36a68ae8764010504857f NCIT_P378 "NCI" @default.
- B10838ad24bd36a68ae8764010504857f type Axiom @default.
- B10838ad24bd36a68ae8764010504857f annotatedProperty IAO_0000115 @default.
- B10838ad24bd36a68ae8764010504857f annotatedSource NCIT_C67041 @default.
- B10838ad24bd36a68ae8764010504857f annotatedTarget "A recombinant, soluble, hexameric fusion protein consisting of three human Fas ligand (FasL) extracellular domains fused to the dimer-forming collagen domain of human adiponectin with potential pro-apoptotic and antineoplastic activities. Assembled into a soluble hexameric structure mimicking the ligand clustering of endogenous active FasL, Fas receptor agonist APO010 activates the Fas receptor, resulting in caspase-dependent apoptosis in susceptible tumor cell populations. FasL is a transmembrane protein of the tumor necrosis factor (TNF) superfamily and a pro-apoptotic ligand for the death receptor Fas." @default.