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- B14c3d836092e4520fc8963e76e3608c4 NCIT_P378 "NCI" @default.
- B14c3d836092e4520fc8963e76e3608c4 type Axiom @default.
- B14c3d836092e4520fc8963e76e3608c4 annotatedProperty IAO_0000115 @default.
- B14c3d836092e4520fc8963e76e3608c4 annotatedSource NCIT_C29013 @default.
- B14c3d836092e4520fc8963e76e3608c4 annotatedTarget "A commercial combination preparation, by Biovail Pharmaceuticals, containing chlorpheniramine maleate, phenylephrine hydrochloride and methscopolamine nitrate used to relieve symptoms of cold and flu. Chlorpheniramine maleate, an antihistamine, blocks the effects of histamine, thereby preventing symptoms such as sneezing and itchy, watery eyes, runny nose and itchy throat. Phenylephrine hydrochloride, a sympathomimetic agent, acts as a decongestant by inducing blood vessels constriction mediated via alpha-adrenergic receptors, thereby reducing blood flow and decreasing swelling which prevents nasal and sinus congestion. Methscopolamine nitrate, an anticholinergic agent, may reduce fluid secretions and provides a drying effect in nose, eyes and chest." @default.