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- B163f0e89f8fa5b397cc2a0a9ac724525 NCIT_P378 "NCI" @default.
- B163f0e89f8fa5b397cc2a0a9ac724525 type Axiom @default.
- B163f0e89f8fa5b397cc2a0a9ac724525 annotatedProperty IAO_0000115 @default.
- B163f0e89f8fa5b397cc2a0a9ac724525 annotatedSource NCIT_C102748 @default.
- B163f0e89f8fa5b397cc2a0a9ac724525 annotatedTarget "A proprietary suspension formulation prepared from granules of standardized extracts from the fruits of Vaccinium myrtillus, the aerial parts of Macleaya cordata and the roots of Echinacea angustifolia, with potential anti-mucositis, anti-inflammatory, and analgesic activities. The main active ingredients of this formulation include anthocyanosides and procyanidins, benzophenanthridinic alkaloids, and alkylamides from V. myrtillus, M. cordata and E. angustifolia extracts, respectively. Upon administration in the mucosal cavity, the anthocyanosides scavenge free radicals, form a protective barrier on the mucosa, and protect the integrity of the capillary vessels; the benzophenanthridine alkaloids prevent the production of pro-inflammatory cytokines by inhibiting NF-kB and may halt the growth of microorganisms; the alkylamides inhibit cyclooxygenase and 5-lipoxygenase thereby blocking productions of prostaglandin and leukotriene. Furthermore, alkylamides modulate the expression of tumor necrosis factor alpha and other cytokines involved in inflammation processes through cannabinoid type 2 receptors and as cannabinomimetics they may also exert analgesic activity." @default.