Matches in Ubergraph for { <https://frink.apps.renci.org/.well-known/genid/B16c866b859e7afa7b2d68dc39e11a477> ?p ?o ?g. }
Showing items 1 to 5 of
5
with 100 items per page.
- B16c866b859e7afa7b2d68dc39e11a477 NCIT_P378 "NCI" @default.
- B16c866b859e7afa7b2d68dc39e11a477 type Axiom @default.
- B16c866b859e7afa7b2d68dc39e11a477 annotatedProperty IAO_0000115 @default.
- B16c866b859e7afa7b2d68dc39e11a477 annotatedSource NCIT_C129555 @default.
- B16c866b859e7afa7b2d68dc39e11a477 annotatedTarget "A ketone and an amino acid derivative that is synthesized by either tryptophan 2,3-dioxygenase (TDO)- or indoleamine 2,3-dioxygenase (IDO)-mediated oxidation of tryptophan with diverse biological functions, including vasodilatory, immunoregulatory and neuromodulatory activities. Kynurenine is a precursor for niacin. Additionally, kynurenine can be further metabolized into anthranilic acid, kynurenic acid, and 3-hydroxykynurenine; aberrant production of kynurenine is associated with neurological disease-related cognitive deficits and depressive symptoms. Overexpressed in certain cancer cell types, kynurenine could potentially be used as a biomarker to assess cancer risk." @default.