Matches in Ubergraph for { <https://frink.apps.renci.org/.well-known/genid/B19a87aa96ca9ed609ca9158e50274d03> ?p ?o ?g. }
Showing items 1 to 5 of
5
with 100 items per page.
- B19a87aa96ca9ed609ca9158e50274d03 NCIT_P378 "NCI" @default.
- B19a87aa96ca9ed609ca9158e50274d03 type Axiom @default.
- B19a87aa96ca9ed609ca9158e50274d03 annotatedProperty IAO_0000115 @default.
- B19a87aa96ca9ed609ca9158e50274d03 annotatedSource NCIT_C92574 @default.
- B19a87aa96ca9ed609ca9158e50274d03 annotatedTarget "A small molecule and androgen receptor (AR) antagonist with potential antineoplastic activity. Apalutamide binds to AR in target tissues thereby preventing androgen-induced receptor activation and facilitating the formation of inactive complexes that cannot be translocated to the nucleus. This prevents binding to and transcription of AR-responsive genes. This ultimately inhibits the expression of genes that regulate prostate cancer cell proliferation and may lead to an inhibition of cell growth in AR-expressing tumor cells." @default.