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- B1a23725f3e4ae8df7cabd10f03e37b44 NCIT_P378 "NCI" @default.
- B1a23725f3e4ae8df7cabd10f03e37b44 type Axiom @default.
- B1a23725f3e4ae8df7cabd10f03e37b44 annotatedProperty IAO_0000115 @default.
- B1a23725f3e4ae8df7cabd10f03e37b44 annotatedSource NCIT_C37452 @default.
- B1a23725f3e4ae8df7cabd10f03e37b44 annotatedTarget "An orally bioavailable semisynthetic analogue of epothilone B with antineoplastic activity. Ixabepilone binds to tubulin and promotes tubulin polymerization and microtubule stabilization, thereby arresting cells in the G2-M phase of the cell cycle and inducing tumor cell apoptosis. This agent demonstrates antineoplastic activity against taxane-resistant cell lines." @default.