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- B1a2b98b72d883bfec9f04aee138876bc NCIT_P378 "NCI" @default.
- B1a2b98b72d883bfec9f04aee138876bc type Axiom @default.
- B1a2b98b72d883bfec9f04aee138876bc annotatedProperty IAO_0000115 @default.
- B1a2b98b72d883bfec9f04aee138876bc annotatedSource NCIT_C66930 @default.
- B1a2b98b72d883bfec9f04aee138876bc annotatedTarget "A class of agents that act by selectively inhibiting angiotensin II receptor activation in the renin-angiotensin-aldosterone system. Angiotensin II receptor antagonists bind to and block the activation of angiotensin II type 1 (AT1) receptors, thereby reducing production and secretion of aldosterone, amongst other actions. The combined effects result in reduction of blood pressure. Although this class of agents is also used in diabetic nephropathy (kidney damage due to diabetes) and congestive heart failure, it is primarily used for the treatment of hypertension in cases where the patient is intolerant of ACE inhibitor therapy." @default.