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- B1c0dc063a6a52757a3387d5f8b24e96c NCIT_P378 "NCI" @default.
- B1c0dc063a6a52757a3387d5f8b24e96c type Axiom @default.
- B1c0dc063a6a52757a3387d5f8b24e96c annotatedProperty IAO_0000115 @default.
- B1c0dc063a6a52757a3387d5f8b24e96c annotatedSource NCIT_C47636 @default.
- B1c0dc063a6a52757a3387d5f8b24e96c annotatedTarget "A recombinant version of the cardiac neurohormone, human B-type natriuretic peptide (hBNP) produced by the ventricular myocardium. Nesiritide binds to natriuretic peptide receptors on vascular smooth muscle and endothelial cells, through which it triggers guanylate cyclase dependent signal transduction resulting in increase of intracellular concentrations of cGMP. This leads to smooth muscle cell relaxation causing arterial and venous dilatation." @default.