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- B1c30fa63f27694cff70b1d4a47d660cc NCIT_P378 "NCI" @default.
- B1c30fa63f27694cff70b1d4a47d660cc type Axiom @default.
- B1c30fa63f27694cff70b1d4a47d660cc annotatedProperty IAO_0000115 @default.
- B1c30fa63f27694cff70b1d4a47d660cc annotatedSource NCIT_C1141 @default.
- B1c30fa63f27694cff70b1d4a47d660cc annotatedTarget "An orally-active agent with potential antineoplastic activity. Carboxyamidotriazole binds to and inhibits non-voltage-operated Ca2+ channels, blocking both Ca2+ influx into cells and Ca2+ release from intracellular stores and resulting in the disruption of calcium channel-mediated signal transduction and inhibition of vascular endothelial growth factor (VEGF) signaling, endothelial proliferation, and angiogenesis. This agent may also inhibit tumor cell growth, invasion and metastasis. (NCI04)" @default.