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- B1dab01e655277198b32aa6318b112e85 NCIT_P378 "NCI" @default.
- B1dab01e655277198b32aa6318b112e85 type Axiom @default.
- B1dab01e655277198b32aa6318b112e85 annotatedProperty IAO_0000115 @default.
- B1dab01e655277198b32aa6318b112e85 annotatedSource NCIT_C68845 @default.
- B1dab01e655277198b32aa6318b112e85 annotatedTarget "An orally active acetate ester form of the steroidal compound abiraterone with antiandrogen activity. Abiraterone inhibits the enzymatic activity of steroid 17alpha-monooxygenase (17alpha-hydrolase/C17,20 lyase complex), a member of the cytochrome p450 family that catalyzes the 17alpha-hydroxylation of steroid intermediates involved in testosterone synthesis. Administration of this agent may suppress testosterone production by both the testes and the adrenals to castrate-range levels." @default.