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- B1e71d03d0edb51688d02d26f9ab1a72f NCIT_P378 "NCI" @default.
- B1e71d03d0edb51688d02d26f9ab1a72f type Axiom @default.
- B1e71d03d0edb51688d02d26f9ab1a72f annotatedProperty IAO_0000115 @default.
- B1e71d03d0edb51688d02d26f9ab1a72f annotatedSource NCIT_C62201 @default.
- B1e71d03d0edb51688d02d26f9ab1a72f annotatedTarget "The deoxycholate salt of amphotericin B, a polyene antifungal antibiotic produced by Streptomyces nodosus, with antifungal activity. Amphotericin B binds to ergosterol, an essential component of the fungal cell membrane. This results in depolarization of the cell membrane, alterations in cell membrane permeability, leakage of important intracellular components, and cell rupture. This agent may also induce oxidative damage in fungal cells and has been reported to stimulate host immune cells." @default.