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- B1f6148346a123bf5936bed27d4a50e9c NCIT_P378 "NCI" @default.
- B1f6148346a123bf5936bed27d4a50e9c type Axiom @default.
- B1f6148346a123bf5936bed27d4a50e9c annotatedProperty IAO_0000115 @default.
- B1f6148346a123bf5936bed27d4a50e9c annotatedSource NCIT_C64761 @default.
- B1f6148346a123bf5936bed27d4a50e9c annotatedTarget "An orally bioavailable small molecule with potential antineoplastic activity. AT7519M selectively binds to and inhibits cyclin dependent kinases (CDKs), which may result in cell cycle arrest, induction of apoptosis, and inhibition of tumor cell proliferation. CDKs are serine/threonine kinases involved in regulation of the cell cycle and may be overexpressed in some types of cancer cells." @default.