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- B1f8a8eafbccf64c5ffafe535e175f6ac NCIT_P378 "NCI" @default.
- B1f8a8eafbccf64c5ffafe535e175f6ac type Axiom @default.
- B1f8a8eafbccf64c5ffafe535e175f6ac annotatedProperty IAO_0000115 @default.
- B1f8a8eafbccf64c5ffafe535e175f6ac annotatedSource NCIT_C107555 @default.
- B1f8a8eafbccf64c5ffafe535e175f6ac annotatedTarget "An active ingredient and one of the glycosides in the traditional Chinese medicine ChanSu; it is also a bufadienolide toxin originally isolated from the venom of the Chinese toad Bufo gargarizans, with potential cardiotonic and antineoplastic activity. Although the mechanism of action of bufalin is still under investigation, this agent is a specific Na+/K+-ATPase inhibitor and can induce apoptosis in cancer cell lines through the activation of the transcription factor AP-1 via a mitogen activated protein kinase (MAPK) pathway." @default.