Matches in Ubergraph for { <https://frink.apps.renci.org/.well-known/genid/B21e565fbdea6ab2e0af0e223e05d9b13> ?p ?o ?g. }
Showing items 1 to 5 of
5
with 100 items per page.
- B21e565fbdea6ab2e0af0e223e05d9b13 NCIT_P378 "NCI" @default.
- B21e565fbdea6ab2e0af0e223e05d9b13 type Axiom @default.
- B21e565fbdea6ab2e0af0e223e05d9b13 annotatedProperty IAO_0000115 @default.
- B21e565fbdea6ab2e0af0e223e05d9b13 annotatedSource NCIT_C733 @default.
- B21e565fbdea6ab2e0af0e223e05d9b13 annotatedTarget "A methylxanthine derivative with hemorrheologic and immunomodulating properties. Pentoxifylline inhibits phosphodiesterase, resulting in increased levels of cyclic adenosine monophosphate (cAMP) in erythrocytes, endothelium, and the surrounding tissues. This leads to vasodilation, improves erythrocyte flexibility, and enhances blood flow. In addition, the increased level of cAMP in platelets inhibits platelet aggregation, which may contribute to a reduction in blood viscosity. This agent also inhibits production of tumor necrosis factor-alpha and interferon-gamma, while it induces Th2-like (T-helper 2) cytokine production, thereby inhibiting Th1-mediated (T-helper 1) inflammatory and autoimmune responses." @default.