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- B22844c5651884ab64282589b24d4cf36 NCIT_P378 "NCI" @default.
- B22844c5651884ab64282589b24d4cf36 type Axiom @default.
- B22844c5651884ab64282589b24d4cf36 annotatedProperty IAO_0000115 @default.
- B22844c5651884ab64282589b24d4cf36 annotatedSource NCIT_C103273 @default.
- B22844c5651884ab64282589b24d4cf36 annotatedTarget "An orally bioavailable, pan fibroblast growth factor receptor (FGFR) inhibitor with potential antineoplastic activity. Upon oral administration, erdafitinib binds to and inhibits FGFR, which may result in the inhibition of FGFR-related signal transduction pathways and thus the inhibition of tumor cell proliferation and tumor cell death in FGFR-overexpressing tumor cells. FGFR, upregulated in many tumor cell types, is a receptor tyrosine kinase essential to tumor cell proliferation, differentiation and survival." @default.