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- B22b9ce516771c2717d0165e479040aa2 NCIT_P378 "NCI" @default.
- B22b9ce516771c2717d0165e479040aa2 type Axiom @default.
- B22b9ce516771c2717d0165e479040aa2 annotatedProperty IAO_0000115 @default.
- B22b9ce516771c2717d0165e479040aa2 annotatedSource NCIT_C173699 @default.
- B22b9ce516771c2717d0165e479040aa2 annotatedTarget "A preparation of autologous T-lymphocytes that have been genetically modified to express a chimeric antigen receptor (CAR) specific for the B-cell maturation antigen (BCMA; tumor necrosis factor receptor superfamily member 17; TNFRSF17), with potential immunostimulating and antineoplastic activities. Upon administration, autologous BCMA-targeted CAR T cells CC-98633 specifically recognize and kill BCMA-expressing tumor cells. BCMA, a tumor specific antigen and a receptor for both a proliferation-inducing ligand (APRIL) and B-cell activating factor (BAFF), is a member of the tumor necrosis factor (TNF) receptor superfamily and plays a key role in plasma cell survival; it is found on the surfaces of plasma cells and overexpressed on malignant plasma cells." @default.