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- B22e585a47792e2994c6089ee415dff2f NCIT_P378 "NCI" @default.
- B22e585a47792e2994c6089ee415dff2f type Axiom @default.
- B22e585a47792e2994c6089ee415dff2f annotatedProperty IAO_0000115 @default.
- B22e585a47792e2994c6089ee415dff2f annotatedSource NCIT_C716 @default.
- B22e585a47792e2994c6089ee415dff2f annotatedTarget "A benzimidazole with selective and irreversible proton pump inhibition activity. Omeprazole forms a stable disulfide bond with the sulfhydryl group of the hydrogen-potassium (H+ - K+) ATPase found on the secretory surface of parietal cells, thereby inhibiting the final transport of hydrogen ions (via exchange with potassium ions) into the gastric lumen and suppressing gastric acid secretion. This agent exhibits no anticholinergic activities and does not antagonize histamine H2 receptors." @default.