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- B233146189fffeca11a1cb62b1cdba09a source "PMID:11523831" @default.
- B233146189fffeca11a1cb62b1cdba09a type Axiom @default.
- B233146189fffeca11a1cb62b1cdba09a annotatedProperty UBPROP_0000003 @default.
- B233146189fffeca11a1cb62b1cdba09a annotatedSource UBERON_0002342 @default.
- B233146189fffeca11a1cb62b1cdba09a annotatedTarget "A well developed neural crest population is present in lampreys (Horigome et al. 1999 ; Tomsa & Langeland, 1999) and gnathostomes. chordate fossils from the early Cambrian (Yunnanozoan and Haikouella) with apparent neural-crest derived structures (pharyngeal denticles and pharyngeal skeletons resembling the striped mucocartilage of the branchial bars in lamprey ammocoete larvae), suggests that neural crest arose very early in vertebrate evolution (Chen et al. 1999; Holland & Chen, 2001). The invertebrate chordates apparently lack defini- tive neural crest. One marker of migrating neural crest in some vertebrates, the antibody HNK1, does not recognize any cells in amphioxus embryos (Holland, unpublished). Even so, in both amphioxus and tunicates, cells at the edges of the neural plate and adjacent nonneural ectoderm share some properties of neural crest[PMID:11523831]" @default.