Matches in Ubergraph for { <https://frink.apps.renci.org/.well-known/genid/B2480aefb91d0962822b67b8be2c0189a> ?p ?o ?g. }
Showing items 1 to 5 of
5
with 100 items per page.
- B2480aefb91d0962822b67b8be2c0189a NCIT_P378 "NCI" @default.
- B2480aefb91d0962822b67b8be2c0189a type Axiom @default.
- B2480aefb91d0962822b67b8be2c0189a annotatedProperty IAO_0000115 @default.
- B2480aefb91d0962822b67b8be2c0189a annotatedSource NCIT_C1311 @default.
- B2480aefb91d0962822b67b8be2c0189a annotatedTarget "A macrolide isolated from Streptomyces tsukubaensis. Tacrolimus binds to the FKBP-12 protein and forms a complex with calcium-dependent proteins, thereby inhibiting calcineurin phosphatase activity and resulting in decreased cytokine production. This agent exhibits potent immunosuppressive activity in vivo and prevents the activation of T-lymphocytes in response to antigenic or mitogenic stimulation. Tacrolimus possesses similar immunosuppressive properties to cyclosporine, but is more potent." @default.