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- B250891348b2cba18d648bef7cb24d37c NCIT_P378 "NCI" @default.
- B250891348b2cba18d648bef7cb24d37c type Axiom @default.
- B250891348b2cba18d648bef7cb24d37c annotatedProperty IAO_0000115 @default.
- B250891348b2cba18d648bef7cb24d37c annotatedSource NCIT_C16507 @default.
- B250891348b2cba18d648bef7cb24d37c annotatedTarget "Drug-, radiation-induced, or spontaneous injuries to DNA that introduce deviations from its normal double-helical conformation. These changes include structural distortions that interfere with replication and transcription, as well as point mutations that disrupt base pairs and exert damaging effects on future generations through changes in DNA sequence. If the damage is minor, it can often be repaired (DNA repair); extensive damage can induce apoptosis." @default.