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- B255a338c5469e8d49548e6a9e0ee9f6d NCIT_P378 "NCI" @default.
- B255a338c5469e8d49548e6a9e0ee9f6d type Axiom @default.
- B255a338c5469e8d49548e6a9e0ee9f6d annotatedProperty IAO_0000115 @default.
- B255a338c5469e8d49548e6a9e0ee9f6d annotatedSource NCIT_C101518 @default.
- B255a338c5469e8d49548e6a9e0ee9f6d annotatedTarget "An orally available nutritional supplement containing high amounts of the vitamin E family member tocotrienol with antioxidant, hypolipidemic and potential immunomodulating and antiproliferative activity. Upon oral administration, tocotrienol-rich fraction (TRF) accumulates in tumor cells and induces cell cycle arrest, programmed cell death, and inhibits tumor cell proliferation. In addition, this agent suppresses 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase activity and inhibits angiogenesis. Rice bran oil, palm oil and annatto seed oil are common sources of TRF." @default.