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- B2644c3e2ef17eb8307567aadb9ed585f NCIT_P378 "NCI" @default.
- B2644c3e2ef17eb8307567aadb9ed585f type Axiom @default.
- B2644c3e2ef17eb8307567aadb9ed585f annotatedProperty IAO_0000115 @default.
- B2644c3e2ef17eb8307567aadb9ed585f annotatedSource NCIT_C76404 @default.
- B2644c3e2ef17eb8307567aadb9ed585f annotatedTarget "An orally bioavailable cyclopentyltriazolopyrimidine, with antiplatelet activity. Upon oral administration, ticagrelor and its major metabolite targets and reversibly binds to the platelet adenosine diphosphate (ADP) P2Y12 receptor (P2Y12R) at a site distinct from that of the endogenous agonist ADP. This blocks the platelet signaling pathway, thereby inhibiting the activation of the glycoprotein complex GPIIb/IIIa, fibrinogen binding to platelets and platelet adhesion and aggregation." @default.