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- B26ad1a37d105006744d8be2bb8810b5c hasDbXref "NCIT:C2915" @default.
- B26ad1a37d105006744d8be2bb8810b5c type Axiom @default.
- B26ad1a37d105006744d8be2bb8810b5c annotatedProperty IAO_0000115 @default.
- B26ad1a37d105006744d8be2bb8810b5c annotatedSource MONDO_0005369 @default.
- B26ad1a37d105006744d8be2bb8810b5c annotatedTarget "A slow growing neuroendocrine tumor, composed of uniform, round, or polygonal cells having monotonous, centrally located nuclei and small nucleoli, infrequent mitoses, and no necrosis. The tumor may show a variety of patterns, such as solid, trabecular, and acinar. Electron microscopy shows small secretory granules. Immunohistochemical studies reveal NSE, as well as chromogranin immunoreactivity. Malignant histology (cellular pleomorphism, hyperchromatic nuclei, prominent nucleoli, necrosis, and mitoses) can occasionally be seen. Such cases may have an aggressive clinical course. Gastrointestinal tract and lung are common sites of involvement." @default.