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- B271fc585661bea4d023913a28b81e6a5 date_retrieved "2012-09-17" @default.
- B271fc585661bea4d023913a28b81e6a5 external_class "VHOG:0001188" @default.
- B271fc585661bea4d023913a28b81e6a5 ontology "VHOG" @default.
- B271fc585661bea4d023913a28b81e6a5 source "DOI:10.1111/j.1469-7580.2005.00472.x Graham A, Okabe M, Quinlan R, The role of the endoderm in the development and evolution of the pharyngeal arches. J Anat (2005)" @default.
- B271fc585661bea4d023913a28b81e6a5 source "http://bgee.unil.ch/" @default.
- B271fc585661bea4d023913a28b81e6a5 type Axiom @default.
- B271fc585661bea4d023913a28b81e6a5 annotatedProperty UBPROP_0000003 @default.
- B271fc585661bea4d023913a28b81e6a5 annotatedSource UBERON_0001132 @default.
- B271fc585661bea4d023913a28b81e6a5 annotatedTarget "The evolution of the tetrapods, and the shift from an aquatic to a terrestrial environment, was believed to have required new controls for regulating calcium homeostasis, and thus the evolution of parathyroid glands (...) both the tetrapod parathyroid and the gills of fish contribute to the regulation of extracellular calcium levels. It is therefore reasonable to suggest that the parathyroid gland evolved as a result of the transformation of the gills into the parathyroid glands of tetrapods and the transition from an aquatic to a terrestrial environment. This interpretation would also explain the positioning of the parathyroid gland within the pharynx in the tetrapod body. Were the parathyroid gland to have emerged de novo with the evolution of the tetrapods it could, as an endocrine organ, have been placed anywhere in the body and still exert its effect.[well established][VHOG]" @default.