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- B2816886f9b3734b9558382a49b04f781 NCIT_P378 "NCI" @default.
- B2816886f9b3734b9558382a49b04f781 type Axiom @default.
- B2816886f9b3734b9558382a49b04f781 annotatedProperty IAO_0000115 @default.
- B2816886f9b3734b9558382a49b04f781 annotatedSource NCIT_C28549 @default.
- B2816886f9b3734b9558382a49b04f781 annotatedTarget "A bivalent DNA vaccine encoding epitopes for both Melan-A (MART-1) and tyrosinase with potential antineoplastic activity. Synchrovax SEM plasmid DNA vaccine contains a plasmid pSEM that encodes 4 epitopes: Melan-A (26-35), Melan-A (31-96), tyrosinase (1-9), and tyrosinase (369-377). Both Melan-A and tyrosinase are tumor antigens associated with melanoma. Vaccination with this plasmid DNA vaccine may induce both humoral and cytotoxic lymphocyte (CTL) responses against cells expressing either or both of these antigens, resulting in decreased tumor growth." @default.