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- B288bc34d808e8de7d1e86f95f6dcb8f5 NCIT_P378 "NCI" @default.
- B288bc34d808e8de7d1e86f95f6dcb8f5 type Axiom @default.
- B288bc34d808e8de7d1e86f95f6dcb8f5 annotatedProperty IAO_0000115 @default.
- B288bc34d808e8de7d1e86f95f6dcb8f5 annotatedSource NCIT_C103820 @default.
- B288bc34d808e8de7d1e86f95f6dcb8f5 annotatedTarget "A fully human monoclonal antibody against killer-cell immunoglobulin-like receptors (KIR), with potential antineoplastic activity. Upon administration, lirilumab binds to KIR, thereby preventing the binding of KIR ligands to KIR on natural killer (NK) cells. By blocking these inhibitory receptors, NK cells become activated and attack cancer cells leading to tumor cell death. KIR, a member of the immunoglobulin superfamily, is expressed on the surface of NK cells." @default.