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- B2975817c5091704ac3bde971bd85dad4 NCIT_P378 "NCI" @default.
- B2975817c5091704ac3bde971bd85dad4 type Axiom @default.
- B2975817c5091704ac3bde971bd85dad4 annotatedProperty IAO_0000115 @default.
- B2975817c5091704ac3bde971bd85dad4 annotatedSource NCIT_C192185 @default.
- B2975817c5091704ac3bde971bd85dad4 annotatedTarget "An analog of nicotinic acid with a hydroxy butyl ketone substituted for the carboxylic acid. 4-hydroxy-1-(3-pyridyl)-1-butanone (HPB or 4-HPB) is formed upon hydrolysis of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and N'-nitrosonornicotine (NNN)-containing DNA and protein adducts. Detection of HPB in certain tissue or cellular samples can be indicative of exposure to tobacco-, tobacco-containing products and the tobacco-specific carcinogenic nitrosamines NNK and NNN." @default.