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- B29879151927cfef54d91ad28376b4272 NCIT_P378 "NCI" @default.
- B29879151927cfef54d91ad28376b4272 type Axiom @default.
- B29879151927cfef54d91ad28376b4272 annotatedProperty IAO_0000115 @default.
- B29879151927cfef54d91ad28376b4272 annotatedSource NCIT_C1878 @default.
- B29879151927cfef54d91ad28376b4272 annotatedTarget "A recombinant analog of the endogenous cytokine erythropoietin, an erythropoiesis-stimulating protein. Due to the addition of two carbohydrate chains, darbepoetin alfa exhibits a three-fold greater half-life than does erythropoietin. Similar to erythropoietin, darbopoietin alfa binds to and activates epoetin receptors, thereby inducing the differentiation and maturation of erythrocyte progenitors, stimulating endothelial cell proliferation, and stimulating B-cell proliferation and immunoglobulin production. (NCI04)" @default.