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- B2a2f9ab97adce7c08b8b1521058e8bfd NCIT_P378 "NCI" @default.
- B2a2f9ab97adce7c08b8b1521058e8bfd type Axiom @default.
- B2a2f9ab97adce7c08b8b1521058e8bfd annotatedProperty IAO_0000115 @default.
- B2a2f9ab97adce7c08b8b1521058e8bfd annotatedSource NCIT_C775 @default.
- B2a2f9ab97adce7c08b8b1521058e8bfd annotatedTarget "The maleate salt form of prochlorperazine, a synthetic, piperazine phenothiazine derivative with antiemetic, antipsychotic, antihistaminic, and anticholinergic activities. Prochlorperazine binds to and blocks the postsynaptic dopamine D2-receptor in the chemoreceptor trigger zone (CTZ) of the brain and may prevent chemotherapy-induced emesis. Prochlorperazine maleate also blocks anticholinergic and alpha-adrenergic receptors. Its antagonistic actions on the alpha-1 adrenergic receptors results in sedation, muscle relaxation, and hypotension." @default.