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- B2a529148ab26feebabb2d33f0c20b2e3 NCIT_P378 "NCI" @default.
- B2a529148ab26feebabb2d33f0c20b2e3 type Axiom @default.
- B2a529148ab26feebabb2d33f0c20b2e3 annotatedProperty IAO_0000115 @default.
- B2a529148ab26feebabb2d33f0c20b2e3 annotatedSource NCIT_C76216 @default.
- B2a529148ab26feebabb2d33f0c20b2e3 annotatedTarget "The pivoxil ester form of a semisynthetic, broad spectrum beta-lactam penicillin with antibacterial activity. Amdinocillin specifically binds to and inactivates penicillin-binding protein 2 (PBP 2) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall, eventually causing cell lysis." @default.