Matches in Ubergraph for { <https://frink.apps.renci.org/.well-known/genid/B2b6a97f078c316b673cc51421d98130c> ?p ?o ?g. }
Showing items 1 to 5 of
5
with 100 items per page.
- B2b6a97f078c316b673cc51421d98130c NCIT_P378 "NCI" @default.
- B2b6a97f078c316b673cc51421d98130c type Axiom @default.
- B2b6a97f078c316b673cc51421d98130c annotatedProperty IAO_0000115 @default.
- B2b6a97f078c316b673cc51421d98130c annotatedSource NCIT_C1044 @default.
- B2b6a97f078c316b673cc51421d98130c annotatedTarget "The hydrochloride salt of the nonsteroidal aromatase inhibitor fadrozole with potential antineoplastic activity. Fadrozole specifically inhibits aromatase, blocking the aromatization of androstenedione and testosterone into estrone and estradiol, respectively, the final step in estrogen biosynthesis; the reduction in estrogen levels may inhibit growth in estrogen-dependent cancers. Aromatase, a member of the cytochrome P-450 superfamily, is found in many tissues; overexpression has been linked to the development of preneoplastic and neoplastic changes in breast tissue." @default.