Matches in Ubergraph for { <https://frink.apps.renci.org/.well-known/genid/B2be0899ba377c831cffc0cf46ebb74a1> ?p ?o ?g. }
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- B2be0899ba377c831cffc0cf46ebb74a1 NCIT_P378 "NCI" @default.
- B2be0899ba377c831cffc0cf46ebb74a1 NCIT_P381 "http://tdcb.nci.nih.gov/cradaopp13.html" @default.
- B2be0899ba377c831cffc0cf46ebb74a1 type Axiom @default.
- B2be0899ba377c831cffc0cf46ebb74a1 annotatedProperty IAO_0000115 @default.
- B2be0899ba377c831cffc0cf46ebb74a1 annotatedSource NCIT_C25986 @default.
- B2be0899ba377c831cffc0cf46ebb74a1 annotatedTarget "Members of the polo subfamily of protein kinases appear to play pivotal roles in cell division and proliferation. These include mammalian Plk, Snk, and Fnk/Prk, Xenopus laevis Plx1, Drosophila melanogaster polo, Schizosaccharomyces pombe Plo1, and Saccharomyces cerevisiae Cdc5. The polo family members are characterized by the presence of a distinct region of homology in the C-terminal non-catalytic domain, termed the polo-box, which is essential for subcellular localization and mitotic functions of the polo kinases. Regulation of polo kinases may be crucial in the control of cell division." @default.