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- B2becaa7e95db73179d90668870387af8 NCIT_P378 "NCI" @default.
- B2becaa7e95db73179d90668870387af8 type Axiom @default.
- B2becaa7e95db73179d90668870387af8 annotatedProperty IAO_0000115 @default.
- B2becaa7e95db73179d90668870387af8 annotatedSource NCIT_C1880 @default.
- B2becaa7e95db73179d90668870387af8 annotatedTarget "The hydrochloride salt of an orally bio-available quinazoline with potential antineoplastic and radiosensitizing activities. Canertinib binds to the intracellular domains of epidermal growth factor receptor tyrosine kinases (ErbB family), irreversibly inhibiting their signal transduction functions and resulting in tumor cell apoptosis and suppression of tumor cell proliferation. This agent also acts as a radiosensitizing agent and displays synergistic activity with other chemotherapeutic agents." @default.