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- B2c40f5b24fe9682df392126f6a95c415 NCIT_P378 "NCI" @default.
- B2c40f5b24fe9682df392126f6a95c415 type Axiom @default.
- B2c40f5b24fe9682df392126f6a95c415 annotatedProperty IAO_0000115 @default.
- B2c40f5b24fe9682df392126f6a95c415 annotatedSource NCIT_C64761 @default.
- B2c40f5b24fe9682df392126f6a95c415 annotatedTarget "An orally bioavailable small molecule with potential antineoplastic activity. AT7519M selectively binds to and inhibits cyclin dependent kinases (CDKs), which may result in cell cycle arrest, induction of apoptosis, and inhibition of tumor cell proliferation. CDKs are serine/threonine kinases involved in regulation of the cell cycle and may be overexpressed in some types of cancer cells." @default.