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- B2c46f250afab395381c2b790571730d1 NCIT_P378 "NCI" @default.
- B2c46f250afab395381c2b790571730d1 type Axiom @default.
- B2c46f250afab395381c2b790571730d1 annotatedProperty IAO_0000115 @default.
- B2c46f250afab395381c2b790571730d1 annotatedSource NCIT_C87288 @default.
- B2c46f250afab395381c2b790571730d1 annotatedTarget "The sulfate salt of vinzolidine, an orally active semisynthetic vinca alkaloid with potential antineoplastic activity. Like other vinca alkaloid compounds, vinzolidine binds to and stabilizes tubulin molecules, thereby interfering with microtubule assembly/disassembly dynamics. As a result, vinzolidine prevents mitotic spindle formation and leads to cell cycle arrest in metaphase." @default.