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- B2d00c98c990592b13b557d98341334d0 NCIT_P378 "NCI" @default.
- B2d00c98c990592b13b557d98341334d0 type Axiom @default.
- B2d00c98c990592b13b557d98341334d0 annotatedProperty IAO_0000115 @default.
- B2d00c98c990592b13b557d98341334d0 annotatedSource NCIT_C2760 @default.
- B2d00c98c990592b13b557d98341334d0 annotatedTarget "A vaccine consisting of microscopic gold particles coated with plasmid DNA encoding the glycoprotein 100 (gp100) melanoma antigen and granulocyte-macrophage colony-stimulating factor (GM-CSF). Vaccination with gp100 and GM-CSF DNA/gold vaccine may stimulate the host immune system to direct cytotoxic T lymphocytes (CTL) against gp100 positive cells, resulting in decreased tumor growth. GM-CSF is thought to increase the induction and activation of antigen-presenting cells (APC), allowing for a reduction in the dose of gp100 administered. (NCI04)" @default.