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- B2d2cabf9f9c59a37f2fcdbbf864bb670 NCIT_P378 "NCI" @default.
- B2d2cabf9f9c59a37f2fcdbbf864bb670 type Axiom @default.
- B2d2cabf9f9c59a37f2fcdbbf864bb670 annotatedProperty IAO_0000115 @default.
- B2d2cabf9f9c59a37f2fcdbbf864bb670 annotatedSource NCIT_C72625 @default.
- B2d2cabf9f9c59a37f2fcdbbf864bb670 annotatedTarget "A semisynthetic, broad-spectrum, beta-lactamase-resistant, third-generation cephalosporin with antibacterial activity. Cefditoren binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis." @default.