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- B2f386f71e27e3a3e13a6c0d0977014bc NCIT_P378 "NCI" @default.
- B2f386f71e27e3a3e13a6c0d0977014bc type Axiom @default.
- B2f386f71e27e3a3e13a6c0d0977014bc annotatedProperty IAO_0000115 @default.
- B2f386f71e27e3a3e13a6c0d0977014bc annotatedSource NCIT_C29128 @default.
- B2f386f71e27e3a3e13a6c0d0977014bc annotatedTarget "The bromide salt form of ipratropium, a synthetic derivative of the alkaloid atropine with anticholinergic properties. Ipratropium antagonizes the actions of acetylcholine at parasympathetic, postganglionic, effector-cell junctions. When inhaled, ipratropium binds competitively to cholinergic receptors in the bronchial smooth muscle thereby blocking the bronchoconstrictor actions of the acetylcholine mediated vagal impulses. Inhibition of the vagal tone leads to dilation of the large central airways resulting in bronchodilation." @default.