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- B2f983613b76c5c34964f7cabd9770349 NCIT_P378 "NCI" @default.
- B2f983613b76c5c34964f7cabd9770349 type Axiom @default.
- B2f983613b76c5c34964f7cabd9770349 annotatedProperty IAO_0000115 @default.
- B2f983613b76c5c34964f7cabd9770349 annotatedSource NCIT_C1004 @default.
- B2f983613b76c5c34964f7cabd9770349 annotatedTarget "A piperidinedione antineoplaston with potential antineoplastic activity. Antineoplaston A10 was originally isolated from human urine but is now synthetically derived. This agent intercalates into DNA, resulting in cell cycle arrest in G1 phase, reduction of mitosis, and decreased protein synthesis. Antineoplaston A10 may also inhibit ras-oncogene expression and activate tumor suppressor gene p53, leading to cell differentiation and apoptosis. (NCI04)" @default.