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- B30500d258d98af18153c41c62d2ad23e NCIT_P378 "NCI" @default.
- B30500d258d98af18153c41c62d2ad23e type Axiom @default.
- B30500d258d98af18153c41c62d2ad23e annotatedProperty IAO_0000115 @default.
- B30500d258d98af18153c41c62d2ad23e annotatedSource NCIT_C82349 @default.
- B30500d258d98af18153c41c62d2ad23e annotatedTarget "A small-molecule inhibitor of Aurora kinases A, B and C with potential antineoplastic activity. Aurora kinase inhibitor AMG 900 selectively binds to and inhibits the activities of Aurora kinases A, B and C, which may result in inhibition of cellular division and proliferation in tumor cells that overexpress these kinases. Aurora kinases are serine-threonine kinases that play essential roles in mitotic checkpoint control during mitosis and are overexpressed by a wide variety of cancer cell types." @default.