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- B30df34cd468f6096f48b5dd0e02c67a9 source "WP" @default.
- B30df34cd468f6096f48b5dd0e02c67a9 type Axiom @default.
- B30df34cd468f6096f48b5dd0e02c67a9 annotatedProperty UBPROP_0000011 @default.
- B30df34cd468f6096f48b5dd0e02c67a9 annotatedSource UBERON_0004035 @default.
- B30df34cd468f6096f48b5dd0e02c67a9 annotatedTarget "The transient fetal subplate zone, together with the marginal zone and the cortical plate, represents the developmental anlage of the mammalian cerebral cortex. It serves as a waiting compartment for growing cortical afferents; its cells are involved in the establishment of pioneering cortical efferent projections and transient fetal circuitry, and apparently have a number of other developmental roles. The subplate zone is a phylogenetically recent structure and it is most developed in the human brain. Subplate neurons are among the first generated neurons in the mammalian cerebral cortex [1]. These neurons disappear during postnatal development and are important in establishing the correct wiring [2][3] and functional maturation [4] of the cerebral cortex. Subplate neurons appear to be selectively sensitive to injury (such as hypoxia) which in humans are associated with motor and cognitive defects" @default.